Webinar: 3Rs Principles Put Into Practice: Animals and Alternatives

Join us for an insightful two-part webinar, featuring expert perspectives on advancing ethical and scientific standards in animal research.

In Part 1 – “Animal Models, 3R Principles, and Alternative In Vitro Models,” Giuliano Grignaschi, Head of the Animal Welfare Office at the University of Milan, will explore the implementation of the 3Rs—Replacement, Reduction, and Refinement—in compliance with European Directive 63/2010. He will discuss the ongoing necessity of using live animals in certain scientific procedures while emphasizing the importance of systematically applying the 3Rs throughout the entire research process. This session will highlight strategies to ensure high standards of animal welfare, including prioritizing alternative methods such as invertebrates and non-animal techniques whenever feasible.

In Part 2 – “How Can We Best Design Pharmacological Experiments to Produce Reliable Data While Complying with the 3Rs” – Fabrizio Gardoni, Professor of Pharmacology at the University of Milan, will address the challenges of designing robust pharmacological experiments that align with the 3Rs principles. His presentation will cover best practices for optimizing experimental design through power analysis, employing innovative alternatives like in vitro models and organ-on-chip systems, and enhancing reproducibility via standardized protocols and open data sharing. Additionally, he will discuss refinement approaches that minimize animal suffering and the integration of cutting-edge technologies—including artificial intelligence and machine learning—to improve data reliability while upholding ethical responsibility.

Together, these complementary presentations provide a comprehensive overview of how the 3Rs can be effectively incorporated into scientific research, balancing the pursuit of knowledge with the highest standards of animal welfare. Don’t miss this opportunity to deepen your understanding of ethical research practices and innovative alternatives in the life sciences